78645

Levetiracetam

analytical standard

• Synonyme(s) : (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetamide, 2(S)-(2-oxopyrrolidin-1-yl)butyramide
• Formule empirique (notation de Hill) : C₈H₁₄N₂O₂
• Numéro CAS: 102767-28-2
• Poids moléculaire : 170.21
• Numéro MDL: MFCD03265610
• Code UNSPSC : 41116107
• ID de substance PubChem : 329768167
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Essai: ≥98.0% (HPLC)
• Activité optique: [α]/D -90±5°, c = 1 in acetone
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; veterinary
• Format: neat
• Chaîne SMILES: CC[C@H](N1CCCC1=O)C(N)=O
• InChI: 1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
• Clé InChI: HPHUVLMMVZITSG-LURJTMIESA-N
• Informations sur le gène: human ... CACNA1B(774) , SV2A(9900)

Description

Description générale

Levetiracetam is an orally active antiepileptic drug, having a high therapeutic index and potential antiepileptogenic and anticonvulsant effects.

Application

Levetiracetam may be used as a reference standard in the determination of levetiracetam in biological fluid samples using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Levetiracetam is a pyrrolidine with antiepileptic activity.

Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

Produits recommandés

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable