49702

Carnosol

analytical standard

• Synonyme(s) : Picrosalvin
• Formule empirique (notation de Hill): C₂₀H₂₆O₄
• Numéro CAS: 5957-80-2
• Poids moléculaire : 330.42
• Numéro MDL: MFCD02752467
• Code UNSPSC : 85151701
• ID de substance PubChem : 329757507
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: Rosemarinus officinalis L. leaves
• Niveau de qualité: 100
• Qualité: analytical standard
• Pureté: ≥98.0% (HPLC)
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): food and beverages
• Format: neat
• Température de stockage: −20°C
• Chaîne SMILES: CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
• InChI: 1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
• Clé InChI: XUSYGBPHQBWGAD-PJSUUKDQSA-N

Description

Description générale

Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.

Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

A phenolic diterpene with antioxidant and anticarcinogenic activities.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

This compound is commonly found in plants of the genus: salvia

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317
• Conseils de prudence: P280 - P302 + P352
• Classification des risques: Skin Sens. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable