410225

Glycine

≥98.5%, for peptide synthesis

• Synonyme(s) : Acide aminoacétique, Acide aminoéthanoïque, Glycocolle
• Formule linéaire : NH₂CH₂COOH
• Numéro CAS: 56-40-6
• Poids moléculaire : 75.07
• Numéro Beilstein : 635782
• Numéro CE : 200-272-2
• Numéro MDL: MFCD00008131
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 24865701
• Nomenclature NACRES : NA.21

Propriétés

• product name: Glycine, ACS reagent, ≥98.5%
• Qualité: ACS reagent
• Niveau de qualité: 200
• Pureté: ≥98.5%
• Forme: powder, crystals or granules
• Impuretés: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• Résidus de calcination: ≤0.1%
• Couleur: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• Pf: 240 °C (dec.) (lit.)
• Traces d'anions: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• Traces de cations: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• Application(s): peptide synthesis
• Chaîne SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clé InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informations sur le gène: rat ... Grin2a(24409)

Description

Description générale

Glycine is the simplest amino acid building block.

Application

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Actions biochimiques/physiologiques

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Neurotransmetteur inhibiteur de la moelle épinière, régulateur allostérique des récepteurs du NMDA.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)