32138

Doripenem monohydrate

VETRANAL^®, analytical standard

• Synonyme(s) : (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• Formule empirique (notation de Hill): C₁₅H₂₄N₄O₆S₂ · H₂O
• Numéro CAS: 364622-82-2
• Poids moléculaire : 438.52
• Numéro Beilstein : 15340136
• Numéro MDL: MFCD09749887
• Code UNSPSC : 41116107
• ID de substance PubChem : 329754061
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Gamme de produits: VETRANAL^®
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; veterinary
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: [H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O
• InChI: 1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• Clé InChI: NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Description

Description générale

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.

Application

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:

• Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
• Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
• Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable