318604
Ammonium chloride-ammonium hydroxide buffer solution
in H2O
Synonyme(s) :
Ammonium Buffer Solution
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About This Item
Numéro MDL:
Code UNSPSC :
12161705
ID de substance PubChem :
Nomenclature NACRES :
NA.21
Produits recommandés
Forme
liquid
Niveau de qualité
Composition
NH4Cl, 1 wt. %
NH4OH, 4 wt. % (pH 10 to 11)
Concentration
in H2O
pH
10-11
Densité
0.99 g/mL at 25 °C
Chaîne SMILES
N.N.O.Cl
InChI
1S/ClH.2H3N.H2O/h1H;2*1H3;1H2
Clé InChI
XEXFVRMLYUDDJY-UHFFFAOYSA-N
Application
Ammonium chloride-ammonium hydroxide buffer solution may be used to crystallize proteins.
Actions biochimiques/physiologiques
Ammonium chloride is the salt component of ammonium chloride-ammonium hydroxide buffer system that completely inhibits the BVDV infection of MDBK cells when present at a concentration of 50 mM . Viruses treated with ammonium chloride (NH4Cl) results in loss of infectivity because it neutralizes the pH of endosome. Hence, viruses with low pH-dependent fusion activity became incapable to fuse their envelope with endosomal membrane.
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Les clients ont également consulté
Thomas Krey et al.
Journal of virology, 79(7), 4191-4200 (2005-03-16)
The route of internalization of the pestivirus bovine viral diarrhea virus (BVDV) was studied by using different chemical and biophysical inhibitors of endocytosis. Expression of the dominant-negative mutant Dyn(K44A) of the GTPase dynamin in MDBK cells, as well as the
A Takada et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(26), 14764-14769 (1998-02-07)
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Multinucleated giant cells (MGCs) are implicated in many diseases including schistosomiasis, sarcoidosis and arthritis. MGC generation is energy intensive to enforce membrane fusion and cytoplasmic expansion. Using receptor activator of nuclear factor kappa-Β ligand (RANKL) induced osteoclastogenesis to model MGC
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