27285

Acide éthylènediaminetétraacétique disodium salt dihydrate

meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

• Synonyme(s) : EDTA disodium salt, EDTA-Na₂, Edétate disodium salt dihydrate, Sequestrene Na₂, Édathamil, Éthylènediaminetétraacétate disodique dihydrate
• Formule empirique (notation de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Numéro CAS: 6381-92-6
• Poids moléculaire : 372.24
• Numéro Beilstein : 3900609
• Numéro CE : 205-358-3
• Code UNSPSC : 12352107
• ID de substance PubChem : 24856480
• Nomenclature NACRES : NA.77

Propriétés

• Agence: tested according to BP; tested according to Ph. Eur.; tested according to USP
• Niveau de qualité: 200
• Conformité réglementaire: tested according to FCC
• Pureté: 99.0-101.0%
• Forme: crystals
• Qualité: meets analytical specification of Ph. Eur., BP, USP, FCC
• Pertinence de la réaction: reagent type: chelator
• Impuretés: residual solvents, complies; ≤0.001% cyanide (CN); ≤0.001% heavy metals (as Pb); ≤0.1% nitrilotriacetic acid (HPLC) (HPLC)
• Perte: 8.7-11.4% loss on drying, 200 °C, 3 h
• pH: 4-5 (20 °C, 5%)
• Pf: 248 °C (dec.) (lit.)
• Solubilité: water: soluble 100 g/L at 20 °C
• Traces d'anions: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• Traces de cations: As: ≤1 mg/kg; Ca:, in accordance; Fe: ≤10 mg/kg; Pb: ≤10 mg/kg
• Application(s): pharmaceutical (small molecule)
• Chaîne SMILES: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• Clé InChI: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Description

Description générale

Ethylenediaminetetraacetic acid disodium salt dihydrate, referred to as EDTA is a widely used chelator of divalent cations like Ca⁺². It can inhibit proteases dependent on metal ions, such as, calcium-dependent cysteine proteases. EDTA also acts as a chelator of the Zn ion, inhibiting metalloproteases that require zinc for activity.

Application

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used along with Na₂HPO4 and citric acid for preparing Na₂EDTA-McIlvaine buffer. Aqueous solution of Ethylenediaminetetraacetic acid disodium salt dihydrate has also been used for photocatalytic hydrogen production

Chélateur de cations divalents. Inhibe les enzymes dont l′activité exige des cations divalents, comme les métalloprotéinases.

Autres remarques

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Informations sur la sécurité

• Pictogrammes: GHS07,GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H332 - H373
• Conseils de prudence: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Classification des risques: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Organes cibles: Respiratory Tract
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)