15523-M

Glycérol

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E422, anhydrous, 99.0-101.0% (alkalimetric)

• Synonyme(s) : 1,2,3-propanetriol, Glycérine
• Formule linéaire : HOCH₂CH(OH)CH₂OH
• Numéro CAS: 56-81-5
• Poids moléculaire : 92.09
• Numéro Beilstein : 635685
• Numéro CE : 200-289-5
• Numéro MDL: MFCD00004722
• Code UNSPSC : 12352104
• ID de substance PubChem : 329750924
• Nomenclature NACRES : NA.21

Propriétés

• Agence: meets analytical specifications of BP; meets analytical specifications of E422; meets analytical specifications of Ph. Eur.; meets analytical specifications of USP
• Niveau de qualité: 100
• Conformité réglementaire: meets analytical specifications of FCC
• Densité de vapeur: 3.1 (vs air)
• Pression de vapeur: <1 mmHg ( 20 °C)
• Qualité: puriss.; meets analytical specification of Ph. Eur., BP, USP, FCC, E422
• Pureté: 99.0-101.0% (alkalimetric); 99.0-101.0% (calc. on H₂O free substance)
• Forme: liquid
• Température d'inflammation spontanée: 698 °F
• Technique(s): IR spectroscopy: suitable; electrophoresis: suitable
• Impuretés: acidity or alkalinity, complies; acrolein, glucose and NH₄-compounds, complies; ester, complies; fatty acids and esters, complies; impurities A and related substances (GC), complies; residual solvents, complies; sugar, complies; ≤0.003% free acid (as CH₃COOH); ≤0.2% 1,2,4-butantriole (GC); ≤10 ppm aldehydes (as HCHO); ≤2% water (Karl Fischer); ≤30 ppm halogen compounds (as Cl); ≤5 ppm heavy metals (as Pb)
• Résidus de calcination: ≤0.01% (as SO₄)
• Indice de réfraction: n20/D 1.471-1.474; n20/D 1.474 (lit.)
• pH: 5.5-8
• Point d'ébullition: 182 °C/20 mmHg (lit.)
• Pf: 20 °C (lit.)
• Densité: 1.2580-1.2644 g/mL at 20 °C; ≥1.257 g/mL at 25 °C; 1.25 g/mL (lit.)
• Chaîne SMILES: OCC(O)CO
• Traces d'anions: chloride (Cl^-): ≤10 ppm; sulfate (SO₄^2-): ≤10 ppm
• Traces de cations: As: ≤1 ppm; Cu: ≤0.001%; Pb: ≤1 ppm; Zn: ≤0.001%
• Adéquation: complies for appearance of solution; complies for reaction against H₂SO₄; corresponds for chromatography; passes test for identity (IR)
• InChI: 1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
• Clé InChI: PEDCQBHIVMGVHV-UHFFFAOYSA-N

Description

Description générale

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Actions biochimiques/physiologiques

Glycerol has been used as

• a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
• a fuel during designing enzymatic biofuel cell.
• a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
• a matrix for fast atom bombardment MS.
• may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 320.0 °F - closed cup
• Point d'éclair (°C): 160 °C - closed cup