03641

Dansyl chloride

for HPLC derivatization, LiChropur^™, ≥99.0% (HPLC)

• Synonyme(s) : 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
• Formule empirique (notation de Hill): C₁₂H₁₂ClNO₂S
• Numéro CAS: 605-65-2
• Poids moléculaire : 269.75
• Numéro Beilstein : 2217205
• Numéro CE : 210-092-6
• Numéro MDL: MFCD00003985
• Code UNSPSC : 41116105
• ID de substance PubChem : 329747747
• Nomenclature NACRES : NA.22

Propriétés

• Qualité: for HPLC derivatization; LiChropur^™
• Niveau de qualité: 100
• Pureté: ≥99.0% (HPLC)
• Forme: powder or crystals
• Technique(s): HPLC: suitable
• Pf: 72-74 °C (lit.)
• Solubilité: acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange
• Température de stockage: 2-8°C
• Chaîne SMILES: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
• Clé InChI: XPDXVDYUQZHFPV-UHFFFAOYSA-N

Description

Description générale

Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.

Application

Dansyl chloride has been used for the fluorogenic labeling of xenoestrogens, 4-nonylphenol and bisphenol A prior to their determination by high-performance liquid chromatography (HPLC) with fluorescence detection. It has also been used for the derivatization of icariin in human serum samples after oral administration of Epimedium decoction, followed by its determination using ultrasensitive LC-tandem mass spectrometry (LC-MS) and for the derivatization of antitumoral agent ES-285 in dog plasma followed by its analysis by HPLC equipped with ultraviolet and fluorescence detection.

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

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Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H290,H314
• Conseils de prudence: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3