MAB5618
Anti-Serotonin Transporter Antibody
ascites fluid, Chemicon®
Synonyme(s) :
SERT
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
ascites fluid
Type de produit anticorps
primary antibodies
Clone
monoclonal
Espèces réactives
primate, human
Ne doit pas réagir avec
rat
Fabricant/nom de marque
Chemicon®
Technique(s)
immunohistochemistry: suitable
Isotype
IgG
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... HTT(3064) , SLC6A4(6532)
Spécificité
Serotonin Transporter, human and non-human primate.
Immunogène
Synthetic peptide from human serotonin transporter.
Application
Anti-Serotonin Transporter Antibody detects level of Serotonin Transporter & has been published & validated for use in IH.
Immunohistochemistry: 1:500-1:1,000 on 10% formalin fixed, paraffin embedded tissue from human Medulla oblongata. Suggested antigen retrieval method is Heat Induced Epitope Retrieval (HIER): Citrate Buffer pH 6.0.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Forme physique
Ascites
Stockage et stabilité
Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Serotonin neurons derived from rhesus monkey embryonic stem cells: similarities to CNS serotonin neurons
Salli, Ugur, et al
Experimental neurology, 188, 351-364 (2004)
Anke J Borgers et al.
Frontiers in neuroscience, 8, 106-106 (2014-05-27)
That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signaling by regulating its availability in the synaptic cleft. The
Smriti Patodia et al.
Brain pathology (Zurich, Switzerland), 32(5), e13074-e13074 (2022-04-29)
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. Reduced medullary serotonergic neurones, modulators of respiration in response to hypercapnia, were reported in
C H Lew et al.
Molecular autism, 11(1), 12-12 (2020-02-07)
Williams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal distribution in key social brain areas, including the prefrontal cortex and the amygdala. The serotonergic
A L Bauman et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(20), 7571-7578 (2000-10-12)
Presynaptic transporter proteins regulate the clearance of extracellular biogenic amines after release and are important targets for multiple psychoactive agents, including amphetamines, cocaine, and antidepressant drugs. Recent studies reveal that dopamine (DA), norepinephrine (NE), and serotonin (5-HT) transporters (DAT, NET
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