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Key Documents

MAB344

Sigma-Aldrich

Anti-O1 Antibody, clone 59

clone 59, Chemicon®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

saturated ammonium sulfate (SAS) precipitated

Clone

59, monoclonal

Espèces réactives

chicken, rat, mouse, human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable

Isotype

IgM

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Spécificité

Recognizes Oligodendrocyte marker O1. Also reacts with certain galactolipids in sperm (see Additional Information library for list).

Immunogène

White matter of corpus callosum from rat brain.

Application

Anti-O1 Antibody, clone 59 is an antibody against O1 for use in IH.
Immunohistochemistry: 10-20 μg/mL on unfixed, shock frozen tissue.

Note: 01 is a lipid which is released from the membrane by alcohol.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Forme physique

Format: Purified
Liquid. Buffer = 0.05 M Potassium Phosphate, 0.3 M NaCl, pH 8.0 with 0.05% sodium azide.

Stockage et stabilité

Maintain lyophilized material at +2–8°C for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
Oligodendrocyte culture, Brain

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Jong-Wan Kim et al.
Folia neuropathologica, 57(1), 24-35 (2019-05-01)
This study was performed to determine whether the disturbed maturation of oligodendrocyte (OL) progenitors might be related to lipopolysaccharide (LPS)-induced hypomyelination. We created organotypic cultures of forebrain slices from neonatal rats and explored the morphological changes of glial cells expressing
Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells.
Karen L Lankford,Masanori Sasaki,Christine Radtke,Jeffery D Kocsis
Glia null
Developmental expression in central and peripheral nervous system of oligodendrocyte cell surface antigens (O antigens) recognized by monoclonal antibodies.
M Schachner et al.
Developmental biology, 83(2), 328-338 (1981-04-30)
Administration of dexamethasone to neonatal rats induces hypomyelination and changes in the morphology of oligodendrocyte precursors.
Kim, JW; Kim, YJ; Chang, YP
Comparative Medicine null
Zhong Liu et al.
Stem cells and development, 26(3), 177-188 (2016-10-21)
Neural stem cells (NSCs) have the capacity to differentiate into neurons, astrocytes, and oligodendrocytes, and therefore represent a promising donor tissue source for treating neurodegenerative diseases and repairing injuries of the nervous system. However, it remains unclear how canonical microRNAs
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