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Key Documents

Autres documents

MAB1978

Sigma-Aldrich

Anti-Integrin αV Antibody, clone LM142

ascites fluid, clone LM142, Chemicon®

Synonyme(s) :

CD51

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

LM142, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG1

Adéquation

not suitable for activity/function inhibition

Numéro d'accès NCBI

NM_002210.2

Numéro d'accès UniProt

P06756

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGAV(3685)

Spécificité

Reactive with integrin alpha-V.

Application

Detect Integrin αV using this Anti-Integrin αV Antibody, clone LM142 validated for use in IP, IH.
Immunohistochemistry (Acetone Fixed Only) 1:1000

Immunofluorescence and immunoprecipitation.

MAB1978 is non-blocking.

Final working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Stockage et stabilité

Maintain at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Réf. du produit
Description
Tarif

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Masako Ueda et al.
Biomaterials, 31(25), 6394-6399 (2010-06-12)
We previously showed that blood outgrowth endothelial cells (BOECs) had a high affinity for polyurethane (PU) covalently configured with cholesterol residues (PU-Chol). However, the molecular mechanisms responsible for this enhanced affinity were not determined. CD47, a multifunctional transmembrane glycoprotein involved
Tatiana Gianni et al.
PLoS pathogens, 9(12), e1003806-e1003806 (2013-12-25)
Herpes simplex virus (HSV)--and herpesviruses in general--encode for a multipartite entry/fusion apparatus. In HSV it consists of the HSV-specific glycoprotein D (gD), and three additional glycoproteins, gH/gL and gB, conserved across the Herpesviridae family and responsible for the execution of
Tobias G Kapp et al.
Scientific reports, 7, 39805-39805 (2017-01-12)
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variety of diseases.
Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes on fibronectin.
L Koivisto, K Larjava, L Hakkinen, V J Uitto, J Heino, H Larjava
Cell Adhesion and Communication null
Adina Borbély et al.
Pharmaceutics, 11(4) (2019-04-04)
Cryptophycins are potent tubulin polymerization inhibitors with picomolar antiproliferative potency in vitro and activity against multidrug-resistant (MDR) cancer cells. Because of neurotoxic side effects and limited efficacy in vivo, cryptophycin-52 failed as a clinical candidate in cancer treatment. However, this
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