MAB1358
Anti-Integrin α6B Antibody, cytoplasmic domain, clone 6B4
clone 6B4, Chemicon®, from mouse
Synonyme(s) :
CD49f
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
6B4, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... ITGA6(3655)
Description générale
Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrin function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha 3 and alpha6, two cytoplasmic variants, A and B, have been identified.
Spécificité
MAB1358 recognizes specifically the cytoplasmic domain of integrin subunit alpha 6B. The antibody stains the basement membrane zone of ducts and acini of salivary gland, kidney tubules, epithelium of colonic crypts and weakly stains sweat glands and sebaceous glands.
Broad species reactivity is expected due to the conserved nature of the epitope.
Broad species reactivity is expected due to the conserved nature of the epitope.
Immunogène
Synthetic Peptide to the cytoplasmic domain of integrin subunit alpha6B including an appending N-terminal cysteine: CSRYDDSVPRYHAVRIRKEEREIKDEKYIDNLEKK
Application
Anti-Integrin α6B Antibody, cytoplasmic domain, clone 6B4 is an antibody against Integrin α6B for use in WB, IC, IH.
Western blotting: 1:100-1:500
Immunocytochemistry: 1:100-1:500 on frozen sections, 1:50-1:100 with avidin-biotin complex detection
Immunocytochemistry
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:100-1:500 on frozen sections, 1:50-1:100 with avidin-biotin complex detection
Immunocytochemistry
Optimal working dilutions must be determined by the end user.
Forme physique
Format: Purified
Stockage et stabilité
Store at 2-8°C, or -20°C in small aliquots for up to 12 months after date of receipt. Avoid freeze/thaw cycles.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Réf. du produit
Description
Tarif
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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