FCMAB404PE

Milli-Mark^® Anti-Tie2/TEK-PE Antibody, clone Ab33

clone Ab33, Milli-Mark^®, from mouse

• Synonyme(s) : Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, hTIE2, p140 TEK, CD202b
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Conjugué: PE
• Forme d'anticorps: purified antibody
• Type de produit anticorps: primary antibodies
• Clone: Ab33, monoclonal
• Espèces réactives: human
• Fabricant/nom de marque: Milli-Mark^®
• Technique(s): flow cytometry: suitable
• Isotype: IgG1κ
• Numéro d'accès NCBI: NP_000450
• Numéro d'accès UniProt: Q02763
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TEK(7010)

Description

Description générale

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin-like loops separated by three epidermal growth factor-like repeats that are connected to three fibronectin type III-like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.

Spécificité

Antibody recognizes Human Tie2/TEK.

Immunogène

Fusion protein corresponding to residues 1-745 of human Tie2/TEK with a C-terminal His6-tag purified from infected SF-9 cells.

Application

Milli-Mark Anti-Tie2/TEK-PE Antibody, clone Ab33 is an antibody against Tie2/TEK for use in FC.

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

Qualité

Evaluated by flow cytometry using HUVEC cells.

Description de la cible

126 kDa Calculated

Forme physique

Protein G Purified

Purified mouse monoclonal IgG1k conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Stockage et stabilité

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Remarque sur l'analyse

Control
HUVEC cells

Informations légales

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable