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Key Documents

CBL2117

Sigma-Aldrich

Anti-Interleukin-6 Antibody, clone B-E8

clone B-E8, Chemicon®, from mouse

Synonyme(s) :

IL-6, B-cell stimulatory factor 2, Interferon beta-2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100
300

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

B-E8, monoclonal

Espèces réactives

human

Ne doit pas réagir avec

mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
neutralization: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Informations sur le gène

human ... IL6(3569)

Catégories apparentées

Spécificité

Recognizes natural and recombinant forms of human Interleukin-6 with an affinity of 0.5 nM. Inhibits IL-6 binding to its receptors and blocks Interleukin-6 induced proliferation on B9 cells.

Immunogène

Recombinant human IL-6.

Application

Blocks Interleukin-6 induced proliferation on B9 cells: 20pg of antibody neutralizes the activity of 1U of IL-6. It is recommended that the sodium azide is removed from the antibody prior to use in this application.

Immunohistochemistry on frozen sections

Optimal working dilutions must be determined by the end user.
Detect Interleukin-6 using this Anti-Interleukin-6 Antibody, clone B-E8 validated for use in ELISA, FC, IH, NEUT.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Liaison

Replaces: 04-1095

Forme physique

Format: Purified
The monoclonal is purified from tissue culture supernatant by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.2.

Stockage et stabilité

Store at 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes.
Tianjiong Lou,Zhongai Zhang,Zhilei Xi,Kang Liu,Lin Li,Baolin Liu,Fang Huang
Inflammation null
Elevated levels of IL-18 in plasma and skeletal muscle in chronic obstructive pulmonary disease.
A M W Petersen,M Penkowa,M Iversen,L Frydelund-Larsen,J L Andersen,J Mortensen,P Lange,B K Pedersen
Lung null
Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise.
Penkowa, M; Keller, C; Keller, P; Jauffred, S; Pedersen, BK
Faseb Journal null
Fang Huang et al.
Biochimie, 94(5), 1143-1150 (2012-02-09)
Puerarin is an isoflavonoid isolated from the root of the plant Pueraria lobata and has been used as a prescribed drug in China for the treatment of cardiovascular diseases in the clinical practice. Puerarin possesses potential therapeutic activities for metabolic
Microglia derived IL-6 suppresses neurosphere generation from adult human retinal cell suspensions.
Balini Balasubramaniam,Debra A Carter,Eric J Mayer,Andrew D Dick
Experimental Eye Research null

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