ABT277

Anti-Galectin-7 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Galectin-7, Gal-7, HKL-14, PI7, p53-induced gene 1 protein
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 300
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Réactivité de l'espèce (prédite par homologie): chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology), monkey (based on 100% sequence homology), baboon (based on 100% sequence homology)
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_001035972
• Numéro d'accès UniProt: P47929
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... LGALS7B(653499)

Description

Description générale

Galectins are a family of carbohydrate binding proteins. Galectin-7 was initially isolated from human keratinocytes as a novel member of S-lectin family that was responsive to retinoic acid but not detectable in epidermal tumors or squamous carcinomas. It is an early transcriptional target of the tumor suppressor P53 and inducible by UV radiation as well. Galectin-7 is also an enhancer of apoptosis, whereas galectin-1 induces tumorigenicity and resistance to apoptosis in several types of cancers. Recent research demonstrates that Galectin-7 acts as an adhesion molecule during implantation, and increased expression of Galectin-7 is associated with miscarriage, thus Galectin-7 is also being studied as a possible biomarker for miscarriage prediction.

Immunogène

KLH-conjugated beta-galactose binding region corresponding to human Galectin-7.

Application

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Galectin-7 in human skin and human larynx tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

This Anti-Galectin-7 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-7.

Qualité

Evaluated by Western Blotting in human skin tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-7 in 10 µg of human skin tissue lysate.

Description de la cible

~16 kDa observed

Forme physique

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to lot specific datasheet.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids