ABN476

Anti-ACVR1C Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, ACVR1C
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès UniProt: Q8NER5
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ACVR1C(130399)

Description

Description générale

Activin receptor type-1 (ACVR1C) is a dimeric growth and differentiation factor belonging to the TKL Ser/Thr protein kinase family. Activins signal through a heteromeric complex of receptor serine kinases which include at least two, type I and two type II receptors. ACVR1C plays an important role in cell differentiation, growth arrest, and apoptosis. It is found in pancreas, heart, colon, small intestine, ovary, hippocampus, medulla oblongata, and putamen of the brain.

Immunogène

KLH-conjugated linear peptide corresponding to human ACVR1C.

Application

Detect Activin receptor type-1 using this rabbit polyclonal antibody, Anti-ACVR1C Antibody validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Qualité

Evaluated by Western Blotting in human placenta tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected ACVR1C in 15 µg of human placenta tissue lysate.

Description de la cible

~62 kDa observed. Uniprot describes 4 isoforms at ~37 kDa, ~46 kDa, ~50 kDa, and ~55 kDa Uncharacterized bands may appear in some lysates.

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human placenta tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable