ABN278

Anti-Prospero homeobox protein 1/PROX1 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: mouse, rat
• Réactivité de l'espèce (prédite par homologie): bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_001257545
• Numéro d'accès UniProt: Q92786
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Prox1(19130)

Description

Description générale

PROX1 (Prospero homeobox protein 1), the homolog of Drosophila Prospero, is a homeobox-containing transcription factor that binds and functions as a co-receptor of liver receptor homolog 1 (LRH1/NR5A2). It is a specific marker for lymphatic endothelial cells, as well as hepatoblasts and hepatocytes. Human Prox1 shares 97% amino acid sequence identity with mouse and rat Prox1.

Immunogène

KLH-conjugated linear peptide corresponding to the C-terminus of human Prospero homeobox protein 1/PROX1.

Application

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Prospero homeobox protein 1/PROX1 in mouse E16 embryo thalamus tissues (Prof. Samual Pleasure, University of California, San Francisco.).

Alexa Fluor^™ is a registered trademark of Life Technologies, Inc.

This Anti-Prospero homeobox protein 1/PROX1 Antibody is validated for use in western blotting & IHC for the detection of Prospero homeobox protein 1/PROX1.

Qualité

Evaluated by Western Blotting in HEK293 nuclear extract.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Prospero homeobox protein 1/PROX1 in 10 µg of HEK293 nuclear extract.

Description de la cible

~95 kDa observed. Uniprot describes a molecular weight at 83 kDa However, this protein may be observed between 80-110 kDa due to sumoylation and/or alternative start sites (Pan, M. R., et al. (2009). J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011). Genes Cells. 16(11):1063-1070.).

Liaison

Replaces: AB5475

Informations légales

ALEXA FLUOR is a trademark of Life Technologies

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable