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Key Documents

AB1846

Sigma-Aldrich

Anti-C-X-C Chemokine Receptor 4 Antibody, NT

Chemicon®, from rabbit

Synonyme(s) :

CD184, CXCR4

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CXCR4(7852)

Spécificité

Recognizes CXCR4, N-terminus.

Immunogène

Amino-terminus peptide of human CXCR4 (Berson, 1996; Leotscher, 1994).
Epitope: N-terminus

Application

Anti-C-X-C Chemokine Receptor 4 Antibody, N-terminus is an antibody against C-X-C Chemokine Receptor 4 for use in IC, IP & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Western blot: 1-2 μg/mL. HeLa cell lysates can be used as positive control. The antibody should detect a band at 40 kDa.

Immunocytochemistry: 10 μg/mL

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Description de la cible

40 kDa

Forme physique

Format: Purified
Protein A purified
Purified IgG in PBS containing 0.02% sodium azide.

Stockage et stabilité

Maintain 1 year at 4°C, from date of shipment. Do not freeze. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
Skin

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke.
Cui, X; Chen, J; Zacharek, A; Li, Y; Roberts, C; Kapke, A; Savant-Bhonsale, S; Chopp, M
Stem Cells null
Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.
Robin, AM; Zhang, ZG; Wang, L; Zhang, RL; Katakowski, M; Zhang, L; Wang, Y; Zhang, C; Chopp, M
Journal of Cerebral Blood Flow and Metabolism null
Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells.
Gu, H; Li, XU; Zhou, C; Wen, Y; Shen, Y; Zhou, L; Li, J
Oncology Letters null
Linhui Wang et al.
Oncology reports, 22(6), 1333-1339 (2009-11-04)
Renal cell carcinoma (RCC) shows organ-specific metastasis. This may be attributed to the fact that the CXCR4 G protein coupled receptor on RCC cells mediates chemo-attraction toward stromal-derived factor (SDF)-1 secreted by target organs. SDF-1 binding to CXCR4 initiates many
Jane D Holland et al.
Cancer research, 66(8), 4117-4124 (2006-04-19)
CXCR4 is a G protein-coupled receptor of considerable biological significance, and among its numerous functions, it is suggested to play a critical role in cancer metastasis. We have investigated the expression and function of CXCR4 in a range of breast

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