AB1690
Anti-Ubiquitin Antibody
serum, Chemicon®
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
serum
Type de produit anticorps
primary antibodies
Clone
polyclonal
Espèces réactives
bovine, eukaryotes, human
Fabricant/nom de marque
Chemicon®
Technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... UBAP2(55833)
Spécificité
Ubiquitin (76 amino acid, 8.5 kDa). Shows staining of neurofibrillary tangles, neurites in senile plaques and a subset of neuronal processes. No reactivity seen to tau, neurofilament or microtubule-associated proteins.
Immunogène
Purified uboquitin covalently coupled to KLH using glutaraldehde.
Application
Anti-Ubiquitin Antibody detects level of Ubiquitin & has been published & validated for use in WB, IH, IH(P).
Immunohistochemistry: 1:1,000-1:5,000. Tissue fixed in 10% formalin, Bouin′s fixative for 1-2 days and embedded in paraffin, or unfixed frozen tissues may be used.
Immunoblotting: 1:1,000-1:5,000.
Optimal working dilutions must be determined by end user.
Immunoblotting: 1:1,000-1:5,000.
Optimal working dilutions must be determined by end user.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
Ubiquitin & Ubiquitin Metabolism
Forme physique
Neat rabbit antisera with 10 mM sodium azide.
Stockage et stabilité
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Certificats d'analyse (COA)
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Identification of Salmonella Typhimurium Deubiquitinase SseL Substrates by Immunoaffinity Enrichment and Quantitative Proteomic Analysis.
Nakayasu, ES; Sydor, MA; Brown, RN; Sontag, RL; Sobreira, TJ; Slysz, GW; Humphrys et al.
Journal of Proteome Research null
Jackalina M Van Kampen
Methods in molecular biology (Clifton, N.J.), 1806, 255-267 (2018-06-30)
Progranulin (PGRN) is a multifunctional protein that is widely expressed throughout the brain, where it has been shown to be a critical regulator of CNS inflammation (Ahmed et al., J Neuroinflammation 4:7, 2007; Yin et al., J Exp Med 207:117-128
Nataša Bauer et al.
Frontiers in plant science, 10, 1469-1469 (2019-12-12)
MATH-BTB proteins are known to act as substrate-specific adaptors of CUL3-based E3 ligases in the ubiquitin proteasome pathway. Their BTB domain binds to CUL3 scaffold proteins and the less conserved MATH domain targets a highly diverse collection of substrate proteins
Intracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278F.
Hatch, NE; Hudson, M; Seto, ML; Cunningham, ML; Bothwell, M
The Journal of Biological Chemistry null
Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization.
Zimmerman, SW; Manandhar, G; Yi, YJ; Gupta, SK; Sutovsky, M; Odhiambo, JF; Powell et al.
Testing null
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