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Key Documents

AB1623

Sigma-Aldrich

Anti-Histone H2B Antibody

serum, Chemicon®

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... H2BC1(255626)

Spécificité

Reacts with histone H2B in human nuclear fractions. No cross-reactivity with other histones, H1, H2A, H3 or H4. Binding of histones from other species has not been tested, but it is likely as the amino acid sequence of histone H2B has been found to be identical in all species examined.

Immunogène

Synthetic peptide

Application

Detect Histone H2B also known as Histone H2B with Anti-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Western blot

Immunohistochemistry on paraformaldehyde treated sections.

Optimal working dilutions must be determined by end user.

Liaison

Replaces: MABE15

Forme physique

Rabbit antiserum. Liquid. Contains no preservative.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Histone H1 is released from myonuclei and present in rimmed vacuoles with DNA in inclusion body myositis.
Satoshi Nakano, Akiyo Shinde, Kengo Fujita, Hidefumi Ito, Hirofumi Kusaka, Satoshi Nakano et al.
Neuromuscular Disorders null
Yinghong Ma et al.
Journal of cell science, 118(Pt 8), 1607-1616 (2005-03-24)
In mammalian heterochromatin, cytosine bases of CpG dinucleotides are symmetrically modified by methylation. Patterns of CpG methylation are maintained by the action of Dnmt1, the mammalian maintenance cytosine methyltransferase enzyme. We genetically manipulated the levels of CpG methylation and found
Ricardo Martinez-Zamudio et al.
Molecular and cellular biology, 32(13), 2490-2502 (2012-05-02)
The packaging of DNA into nucleosomes imposes obstacles on gene transcription, and histone-modifying and nucleosome-remodeling complexes work in concert to alleviate these obstacles so as to facilitate transcription. Emerging evidence shows that chromatin-associated poly(ADP-ribose) polymerase 1 (PARP-1) and its enzymatic
Daniel R Arnold et al.
Developmental biology, 313(1), 347-358 (2007-11-27)
Growing oocytes accumulate mRNAs and proteins that support early embryogenesis. Among the most abundant of these maternal factors are the histones. Histone mRNA accumulation and translation are mainly restricted to S-phase in somatic cells, and the mechanism by which oocytes
Siwei Ouyang et al.
Neurobiology of aging, 36(10), 2850-2860 (2015-08-11)
The progressive loss of neurons causes neurodegenerative diseases. Because the accumulation of DNA breaks results in neuronal apoptosis, the lack of a variety of DNA damage repair-related proteins contributes to neurodegeneration. The ubiquitin ligase RNF8 plays an important role in

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