AB10535

Anti-Neurogenin-3 (rabbit) Antibody

serum, from rabbit

• Synonyme(s) : Neurogenin 3, NGN3, Neurogenin3
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: serum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: mouse
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Isotype: IgG
• Numéro d'accès NCBI: NP_033849
• Numéro d'accès UniProt: P70661
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Neurog3(11925)

Description

Description générale

Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (mash1 is essential for noradrenergic differentiation). Neurogenin-3 also promotes pancreatic development.

Spécificité

This antibody recognizes Neurogenin-3 at the N-terminus.

Immunogène

Epitope: N-terminus

GST-tagged recombinant protein corresponding to the N-terminus of mouse Neurogenin-3.

Application

Detect Neurogenin-3 (rabbit) using this Anti-Neurogenin-3 (rabbit) Antibody validated for use in WB, IH.

Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Neurogenin-3 in mouse embryo E12.5+ tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Qualité

Evaluated by Western Blot in mNgn3 transfected and wildtype rabbit reticulocyte lysates.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Neurogenin-3 on 10 µg of mNgn3 transfected rabbit reticulocyte lysates.

Description de la cible

32 kDa

Forme physique

Unpurified

Unpurified rabbit polyclonal serum containing 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Remarque sur l'analyse

Control
mNgn3 transfected and wildtype rabbit reticulocyte lysates

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1