8.52339

Fmoc-Pen(Trt)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonyme(s) : Fmoc-Pen(Trt)-OH, Fmoc-α, α-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine
• Formule empirique (notation de Hill): C₃₉H₃₅NO₄S
• Numéro CAS: 201531-88-6
• Poids moléculaire : 613.76
• Numéro MDL: MFCD00237388
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• product name: Fmoc-Pen(Trt)-OH, Novabiochem^®
• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥98% (TLC); ≥98.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Groupe fonctionnel: thiol
• Température de stockage: 15-25°C
• InChI: 1S/C39H35NO4S/c1-38(2,45-39(27-16-6-3-7-17-27,28-18-8-4-9-19-28)29-20-10-5-11-21-29)35(36(41)42)40-37(43)44-26-34-32-24-14-12-22-30(32)31-23-13-15-25-33(31)34/h3-25,34-35H,26H2,1-2H3,(H,40,43)(H,41,42)/t35-/m1/s1
• Clé InChI: XSGMGAINOILNJR-PGUFJCEWSA-N

Description

Description générale

Fmoc-Pen(Trt)-OH is the standard building block for the introduction of penicillamine amino-acid residues by Fmoc SPPS. The side-chain thiol protecting group (Trt) is removed during the standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles:
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

Fmoc-Pen(Trt)-OH has been recently used in the synthesis of disulfide surrogate peptides.

Remarque sur l'analyse

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable