8.52062

Fmoc-Tic-OH

Novabiochem^®

• Synonyme(s) : Fmoc-Tic-OH, N-1-Fmoc-L-1,2,3,4,-tetrahydro-isoquinoline-3-carboxylic acid
• Formule empirique (notation de Hill): C₂₅H₂₁NO₄
• Numéro CAS: 136030-33-6
• Poids moléculaire : 399.44
• Numéro MDL: MFCD00144368
• Code UNSPSC : 12352209

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥97.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Groupe fonctionnel: Fmoc
• Température de stockage: 15-25°C
• InChI: 1S/C25H21NO4/c27-24(28)23-13-16-7-1-2-8-17(16)14-26(23)25(29)30-15-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h1-12,22-23H,13-15H2,(H,27,28)/p-1/t23-/m0/s1
• Clé InChI: LIRBCUNCXDZOOU-QHCPKHFHSA-M

Description

Description générale

Standard building block for introduction of Tic amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

^[1] M. Vincent, et al. (1982) Tetrahedron Lett., 16, 1677.
^[2] P. L. Julian, et al. (1984) J. Am. Chem. Soc., 79, 180.
^[3] W. A. Kazmierski, et al. (1988) Tetrahedron Lett., 44, 697.

Liaison

Replaces: 04-12-1130

Remarque sur l'analyse

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable