8.51021

N₃-(PEG)₇-COOH (33 atoms)

Novabiochem^®

• Synonyme(s) : N₃-(PEG)₇-COOH (33 atoms), O-(2-Azidoethyl)-O′-(N-diglycolyl-2-aminoethyl)-heptaethyleneglycol
• Formule empirique (notation de Hill): C₂₂H₄₂N₄O₁₂
• Numéro CAS: 846549-37-9
• Poids moléculaire : 554.59
• Numéro MDL: MFCD10001327
• Code UNSPSC : 12352106
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 400
• Gamme de produits: Novabiochem^®
• Pureté: ≥97.0% (HPLC)
• Forme: oil
• Capacité de réaction: reaction type: click chemistry
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Température de stockage: 2-8°C
• InChI: 1S/C22H42N4O12/c23-26-25-2-4-31-6-8-33-10-12-35-14-16-37-18-17-36-15-13-34-11-9-32-7-5-30-3-1-24-21(27)19-38-20-22(28)29/h1-20H2,(H,24,27)(H,28,29)
• Clé InChI: WWDNBBVPYDZICO-UHFFFAOYSA-N

Description

Description générale

This building block is prepared from highly purified PEG to ensure homogeneous products free from contaminating PEG oligomers. In this derivative the azido group acts as an orthogonally masked amine; it is stable to both TFA and piperidine but is easily converted to an amine by treatment with phosphines or thiols. For a similar spacer, see reference ^[1]. This material is now only available as an oil.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references
^[1] J. Mack, et al. (1999) J. Peptide Sci., 6, 135.

Liaison

Replaces: 01-63-0103

Remarque sur l'analyse

Color (visual): slight yellow to yellow
Appearance of substance (visual): oil
Assay (HPLC, area%): ≥ 97.0 % (a/a)

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315 - H319 - H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable