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Sigma-Aldrich

Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6)

liquid, clone 272-17E6, Calbiochem®

Synonyme(s) :

Anti-CD51

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.43

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

272-17E6, monoclonal

Forme

liquid

Contient

≤0.1% sodium azide as preservative

Espèces réactives

human

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG1

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGAV(3685)

Description générale

Purified mouse monoclonal antibody. Recognizes the αv integrin chain and all αv-containing integrins.
Recognizes the αv integrin chain and all αv-containing integrins.
This Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin αv (Ab-1).

Immunogène

Human
human placental αvβ₃ integrin

Application

Cell Inhibition Assays (see application reference)

ELISA (see application reference)

Flow Cytometry (2.5 µg/ml, see application reference)

Immunoprecipitation (2.5 µg/ml, see application reference)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In PBS, pH 7.6.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Autres remarques

Akiyama, S.K. 1996. Hum. Cell9, 181.
Hynes, R.O. 1992. Cell69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell45, 549.
Cross-reacts with all αv integrins. Blocks cell adhesion mediated by all αv integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Colin D H Ratcliffe et al.
Traffic (Copenhagen, Denmark), 17(6), 670-688 (2016-03-05)
The integrin family of cell adhesion receptors link extracellular matrices to intracellular signaling pathways and the actin cytoskeleton; and regulate cell migration, proliferation and survival in normal and diseased tissues. The subcellular location of integrin receptors is critical for their
Lan Nguyen et al.
Journal of biomolecular screening, 17(6), 835-842 (2012-04-05)
Alzheimer's disease (AD) is a devastating neurodegenerative disease affecting millions of people. The amyloid hypothesis suggests that the pathogenesis of AD is related to the accumulation of amyloid beta (Aβ) in the brain. Herein, the authors quantify Aβ-mediated changes in
Abdullah Karadag et al.
Cancer research, 65(24), 11545-11552 (2005-12-17)
The up-regulation of various matrix metalloproteinases (MMP), certain cell receptors such as integrins and CD44, and the SIBLING family of integrin-binding glycophosphoproteins have been reported separately and in various combinations for many types of tumors. The mechanisms by which these

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