264151

Caspase-3 Substrate VII, Fluorogenic

Fluorogenic caspase-3 substrate.

• Synonyme(s) : Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC
• Formule empirique (notation de Hill): C₃₀H₃₄F₃N₅O₁₃
• Poids moléculaire : 729.61
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: lyophilized solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated; protect from light
• Couleur: white
• Solubilité: DMSO: 5 mg/mL
• Fluorescence: λ_ex ~400 nm; λ_em ~505 nm
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.

Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Fluorogenic caspase-3 substrate

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Séquence

Ac-Asp-Glu-Val-Asp-AFC

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable