218753

Caspase-5 Inhibitor I

Single spot by TLC, solid, Caspase-5 inhibitor, Calbiochem^®

• Synonyme(s) : Caspase-5 Inhibitor I, Z-WE(OMe)HD(OMe)-FMK
• Formule empirique (notation de Hill): C₃₇H₄₂FN₇O₁₀
• Poids moléculaire : 763.77
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
• Niveau de qualité: 100
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated
• Couleur: white
• Solubilité: DMSO: 5 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICE_rel-III, TY), as well as caspase-1 and caspase-4.

A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.

Actions biochimiques/physiologiques

Cell permeable: yes

Primary Target
caspase-1, caspase-4, caspase-5, caspase-8

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Séquence

Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*

Forme physique

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.

Remarque sur l'analyse

single spot by TLC

Autres remarques

Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable