1.07164

Paraffin pastilles

solidification point about 56-58°C for histology

• Synonyme(s) : Paraffin pastilles, Paraffin pastilles solidification point, Paraffin for Histology
• Numéro CAS: 64742-51-4
• Code UNSPSC : 41116124
• Numéro de classement CE : 265-154-5
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 200
• Forme: solid
• Puissance: >5000 mg/kg LD₅₀, oral (Rat); >3000 mg/kg LD₅₀, skin (Rabbit)
• IVD: for in vitro diagnostic use
• Couleur: white
• kinematic viscosity: 4.2 cSt(100 °C)
• Température de transition: flash point >100 °C
• Densité: 0.9 g/cm³ at 20 °C
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: 15-25°C

Description

Description générale

Paraffin pastilles - solidification point about 56-58 °C for histology, are a highly pure ready-to-use paraffin product. Paraffins are the materials generally used to embed the specimens for histological applications. In order to achieve uniformous ribbon-sectioning quality, defined hardness and homogeneity of the processed material is necessary. This can be guarranteed through high-quality raw materials and defined melting points. The melting point of Paraffin is 56-58°C. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU).

Application

• Clinical application of targeted tumour sequencing tests for detecting ERBB2 amplification and optimizing anti-HER2 therapy in gastric cancer.: This study demonstrates the use of paraffin-embedded tissue samples in targeted tumor sequencing to identify patients suitable for anti-HER2 therapy, highlighting paraffin′s utility in preserving sample integrity for genetic analysis (Ichikawa et al., 2024).


• Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker.: Describes a novel proteomics method using formalin-fixed paraffin-embedded (FFPE) samples to identify biomarkers for hormone-induced changes in cellular structures, advancing tissue-specific molecular diagnostics (Faktor et al., 2024).


• TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.: Introduces TSWIFT, a new technique for the iterative staining of paraffin-embedded human brain sections, providing enhanced imaging capabilities for neurological research (Porter et al., 2024).


• [Optimal melanin removal methods for HE staining, immunohistochemistry and molecular detection].: Investigates various methods for melanin removal in HE staining processes involving paraffin-embedded samples, crucial for accurate histopathological and immunohistochemical analyses (Zhang et al., 2024).


• Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw.: This case report utilizes paraffin-embedded sections to uncover novel histopathological insights into osteonecrosis, demonstrating paraffin′s role in detailed structural analysis in pathological conditions (Koizumi et al., 2024).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable