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Key Documents

07-045

Sigma-Aldrich

Anti-HDAC5 Antibody

Upstate®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

mouse, human, rat

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... HDAC5(10014)

Spécificité

HDAC5

Immunogène

KLH-conjugated synthetic peptides corresponding to amino acids 536-545 and 194-206 (C-TKTGELPRQP and C-KSKEPTPGGLNHS) of human HDAC5

Application

Detect HDAC5 also known as histone deacetylase 5 with Anti-HDAC5 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Weaker staining noticed in mouse and rat versus human.

Qualité

routinely evaluated by immunoblot on HeLa nuclear extract or HeLa whole cell lysate

Description de la cible

160 kDa

Forme physique

0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide.
Format: Purified
Protein A chromatography

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis.
Sian H Leech,Caroline A Evans,Leila Shaw,Chi H Wong,Joanne Connolly,John R Griffiths et al.
Proteomics null
Hongbo Ling et al.
Cell cycle (Georgetown, Tex.), 11(20), 3779-3791 (2012-10-02)
Centrosome duplication is controlled both negatively and positively by a number of proteins. The activities and stabilities of those regulatory proteins are in many cases controlled by posttranslational modifications. Although acetylation and deacetylation are highly common posttranslational modifications, their roles
Lauren E Kernochan et al.
Human molecular genetics, 14(9), 1171-1182 (2005-03-18)
Increasing survival motor neuron 2 (SMN2) gene expression may be an effective strategy for the treatment of spinal muscular atrophy (SMA). Histone deacetylase (HDAC) inhibitors have been shown to increase SMN transcript and protein levels, but the specific role of
Oliver H Krämer et al.
The EMBO journal, 22(13), 3411-3420 (2003-07-04)
Histone-modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. Selective modulators of HDAC isoenzymes could serve as efficient
Syed A H Zaidi et al.
Investigative ophthalmology & visual science, 61(11), 17-17 (2020-09-12)
We determined whether δ-opioid receptor agonist (SNC-121) regulates acetylation homeostasis via controlling histone deacetylases (HDACs) activity and expression in optic nerve head (ONH) astrocytes. ONH astrocytes were treated with SNC-121 (1 µM) for 24 hours. The HDAC activity was measured

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