06-867
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody
serum, Upstate®
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
serum
Type de produit anticorps
primary antibodies
Clone
polyclonal
Espèces réactives
rat, human, mouse
Fabricant/nom de marque
Upstate®
Technique(s)
western blot: suitable
Isotype
IgG
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
phosphorylation (pSer726)
Informations sur le gène
human ... STAT5A(6776)
Spécificité
phosphorylated STAT5A (S726) and STAT5B (S731), does not recognize STAT5B containing a S731A mutation
Immunogène
peptide (DQAP[pS]PAVC) corresponding to amino acids 722-730 of human STAT5A or 727-735 of human STAT5B
Application
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody is a rabbit polyclonal antibody for detection of phospho-STAT5A/B (Ser726/Ser731) also known as signal transducer & activator of transcription 5A/B & has been tested in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Qualité
routinely evaluated by immunoprecipitating STAT5A from RIPA lysates of Nb2-Sp cells that had been treated with prolactin; subsequent immunoblotting was performed using Anti-STAT5A (Catalog #06-968)
Description de la cible
94kDa
Forme physique
Antiserum
rabbit antiserum in 30% glycerol and 0.05% sodium azide
Stockage et stabilité
2 years at -20°C
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Development of pure prolactin receptor antagonists.
Bernichtein, S; Kayser, C; Dillner, K; Moulin, S; Kopchick, JJ; Martial, JA; Norstedt et al.
The Journal of Biological Chemistry null
Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase.
Kirken, R A, et al.
The Journal of Biological Chemistry, 272, 15459-15465 (1997)
P L Bergad et al.
The Journal of biological chemistry, 275(11), 8114-8120 (2000-03-14)
A growth hormone-inducible nuclear factor complex (GHINF), affinity-purified using the growth hormone response element (GHRE) from the promoter of rat serine protease inhibitor 2.1, was found to contain Stat5a and -5b, as well as additional components. The ubiquitous transcription factor
H Yamashita et al.
The Journal of biological chemistry, 273(46), 30218-30224 (1998-11-07)
Transcription factors of the Stat family are controlled by protein kinases. Phosphorylation of a positionally conserved tyrosine residue is obligatory for Stat dimerization, nuclear translocation, and specific DNA binding. Studies of Stat1 and Stat3 have suggested that serine phosphorylation may
R A Kirken et al.
The Journal of biological chemistry, 272(22), 14098-14103 (1997-05-30)
Transcription factors of the Stat gene family are selectively activated by many hormones and cytokines. Stat5 originally was cloned as a prolactin-stimulated DNA-binding protein, but is also activated by non-lactogenic cytokines in many cell types. The recent identification of two
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