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Key Documents

06-709

Sigma-Aldrich

Anti-Gq/11α Antibody, CT

Upstate®, from rabbit

Synonyme(s) :

Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, mouse

Fabricant/nom de marque

Upstate®

Technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GNA11(2767)
mouse ... Gna11(14672)

Spécificité

Gqα and G11α

Immunogène

peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α

Application

Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.

Qualité

routinely evaluated by immunoblot on rat brain microsomal preparation

Description de la cible

42kDa

Forme physique

Format: Purified
PBS, pH 7.4
Protein A chromatography

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Blanc, E M, et al.
Journal of Neurochemistry, 69, 570-580 (1997)
Justyna Róg et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(6), 1138-1151 (2019-01-27)
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at the earlier
P Cuq et al.
European journal of pharmacology, 315(2), 213-219 (1996-11-14)
The nature of the pertussis toxin-insensitive G-protein involved in muscarinic-mediated phosphoinositides breakdown and contraction of isolated smooth muscle cells from the circular layer of the rabbit caecum was investigated. Immunoblotting of membrane proteins using affinity purified antibodies directed against different
M Côté et al.
Endocrinology, 138(8), 3299-3307 (1997-08-01)
In 3-day primary cultures of rat glomerulosa cells, a 30-min pre-incubation with either 10 microM colchicine (a microtubule-disrupting agent) or 10 microM cytochalasin B (a microfilament-disrupting agent) decreased angiotensin II (Ang II)-induced inositol phosphate accumulation by 50%. Moreover, both drugs
B Kühn et al.
Molecular endocrinology (Baltimore, Md.), 10(12), 1697-1707 (1996-12-01)
In several cell systems histamine has been shown to stimulate both adenylyl cyclase and phospholipase C through activation of a G protein-coupled H2 receptor. To analyze the bifurcating signal emanating from the activated H2 receptor and to identify the G

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