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M-906

17α-Methyltestosterone solution

Name: 17α-Methyltestosterone solution
Brand: CERILLIAN

1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant^®

Synonyme(s) :

17α-Methyl-4-androsten-17β-ol-3-one solution, 17β-Hydroxy-17α-methyl-4-androsten-3-one solution, Mesterone solution, Methyltestosterone solution

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About This Item

Formule empirique (notation de Hill):

C₂₀H₃₀O₂

Numéro CAS:

58-18-4

Poids moléculaire :

302.45

Numéro Beilstein :

2057425

Numéro MDL:

MFCD00003655

Code UNSPSC :

41116107

ID de substance PubChem :

329818080

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike^®/Snap-N-Shoot^®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant^®

Concentration

1.0 mg/mL in 1,2-dimethoxyethane

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES

C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C20H30O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h12,15-17,22H,4-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

Clé InChI

GCKMFJBGXUYNAG-HLXURNFRSA-N

Informations sur le gène

human ... AR(367)

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Catégories apparentées

Médicaments, drogues illicites et biomarqueurs diagnostiques

Matériaux de référence certifiés

Description générale

17α-Methyltestosterone is an androgenic steroid used in the treatment of testosterone deficiency. 17a-Methyltestosterone is abused in sports as a performance-enhancing drug. This analytical reference standard is applicable for use in sports testing, endocrinology, urine drug testing, or forensic analysis by LC-MS/MS or GC/MS.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Danger

Mentions de danger

H225 - H315 - H332 - H350 - H360FD

Conseils de prudence

P202 - P210 - P233 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313

Classification des risques

Acute Tox. 4 Inhalation - Carc. 1B - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Risques supp

EUH019

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

28.4 °F - closed cup

Point d'éclair (°C)

-2 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Freshwater mudsnail (Potamopyrgus antipodarum) estrogen receptor: identification and expression analysis under exposure to (xeno-)hormones.

Daniela Stange et al.

Ecotoxicology and environmental safety, 75(1), 94-101 (2011-09-29)

Molluscs are raising attention as ecotoxicological test organisms due to their high diversity and ecological importance. The ovoviviparous prosobranch gastropod Potamopyrgus antipodarum (freshwater mudsnail) responds very sensitively to xenobiotics and has therefore been proposed as OECD standard test organism. Endocrine

Development of a fast screening and confirmatory method by liquid chromatography-quadrupole-time-of-flight mass spectrometry for glucuronide-conjugated methyltestosterone metabolite in tilapia.

Kande Amarasinghe et al.

Journal of agricultural and food chemistry, 60(20), 5084-5088 (2012-05-03)

This paper describes the development of a fast method to screen and confirm methyltestosterone 17-O-glucuronide (MT-glu) in tilapia bile. The method consists of solid-phase extraction (SPE) followed by high-performance liquid chromatography-mass spectrometry. The system used was an Agilent 6530 Q-TOF

Molecular identification of an androgen receptor and its changes in mRNA levels during 17α-methyltestosterone-induced sex reversal in the orange-spotted grouper Epinephelus coioides.

Yu Shi et al.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 163(1), 43-50 (2012-05-15)

Androgens play a crucial role in sex differentiation, sexual maturation, and spermatogenesis in vertebrates. The action of androgens is mediated via androgen receptors (ARs). The present study reports the cloning of the cDNA sequence of the ar in the orange-spotted

Introduction of modern endocrine techniques for the production of monosex population of fishes.

Atul K Singh

General and comparative endocrinology, 181, 146-155 (2012-10-16)

Of the techniques available to mass-produce a sterile or monosex population, the hormonal induction of sex reversal is the most widely practiced. This paper presents the synthesis of works done on sex reversal using 17α methyltestosterone (17αMT), 17β estradiol, non-steroidal

Alternative long-term markers for the detection of methyltestosterone misuse.

C Gómez et al.

Steroids, 78(1), 44-52 (2012-11-07)

Methyltestosterone (MT) is one of the most frequently detected anabolic androgenic steroids in doping control analysis. MT misuse is commonly detected by the identification of its two main metabolites excreted as glucuronide conjugates, 17α-methyl-5α-androstan-3α,17β-diol and 17α-methyl-5β-androstan-3α,17β-diol. The detection of these

Afficher tous les articles scientifiques apparentés

Articles

LC/MS/MS Analysis of Testosterone and Metabolites on Ascentis® Express C18

Separation of Testosterone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; 17α-Methyltestosterone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material; 5α-Dihydrotestosterone (DHT) solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; 6β-Hydroxytestosterone solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material

Protocoles

LC/MS/MS Analysis of Steroid Hormones in Plasma

The conversion of clinical methods to LC/MS/MS offers advantages; however, is accompanied by a few limitations, notably interference effects from the endogenous sample matrix.

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