E-011

(1S,2R)-(+)-Ephedrine hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Synonyme(s) : (1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride
• Formule linéaire : C₆H₅CH[CH(NHCH₃)CH₃]OH · HCl
• Numéro CAS: 24221-86-1
• Poids moléculaire : 201.69
• Numéro Beilstein : 6118541
• Numéro CE : 200-659-6
• Numéro MDL: MFCD00064551
• Code UNSPSC : 41116107
• ID de substance PubChem : 329798943
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in methanol (as free base)
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Pf: 218-220 °C (lit.)
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: Cl[H].CN[C@H](C)[C@@H](O)c1ccccc1
• InChI: 1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1
• Clé InChI: BALXUFOVQVENIU-GHXDPTCOSA-N

Description

Description générale

Ephedrine is a methamphetamine analog commonly used as a stimulant and appetite suppressant. It is also found as an active constituent in herbs used for traditional Chinese medicine, such as má huáng. This certified reference standard can be used Snap-N-Spike^® as a starting material in the preparation of calibrators or controls for clinical or forensic applications or Snap-N-Shoot^® in quality control testing of dietary supplements containing ephedrine.

Application

• Efficacy of Ceftiofur in Dairy Cow Metritis: A randomized controlled trial evaluated systemic ceftiofur for metritis therapy in dairy cows, demonstrating significant efficacy in curing metritis, which is crucial for improving reproductive outcomes and milk production. This highlights ceftiofur′s role in veterinary medicine for treating bacterial infections in livestock (Menta et al., 2024).


• Pharmacodynamic Modeling: A study on the predictive modeling of phenotypic antimicrobial susceptibility based on beta-lactamase resistance genes provides insights into the mechanisms of action of ceftiofur hydrochloride, suggesting ways to enhance its clinical effectiveness against resistant bacterial strains (Rahman et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup