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LM1000

Avanti

12:0-13:0 PC

Avanti Research™ - A Croda Brand LM1000, methanol solution

Synonyme(s) :

1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C33H66NO8P
Numéro CAS:
1246304-45-9
Poids moléculaire :
635.85
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

methanol solution

Conditionnement

pkg of 1 × 1 mL (LM1000-1EA)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand LM1000

Concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O

Description générale

Phospholipids are major structural biomolecules found in biological membranes. Phosphocholine (PC) is an intermediate of phosphatidylcholine synthesis catalyzed by choline kinase.

Application

12:0-13:0 PC or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine has been used:
  • as an internal standard in liquid chromatography/mass spectrometry (LC/MS) analysis
  • as a lipid standard for phospholipid quantification by MS
  • as an internal standard for the retention time recalibration during LC-MS data processing
  • as an MS grade lipid standard for lipid extraction from macrophages

Actions biochimiques/physiologiques

Phospholipids participate in protein mediated intracellular and extracellular signaling processes.

Conditionnement

2 mL Amber Glass Sealed Ampule (LM1000-1EA)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Souvent commandé avec ce produit

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Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Akifumi Shiomi et al.
Bioscience, biotechnology, and biochemistry, 84(3), 583-593 (2019-11-26)
Fish cell lines are widely used for the studies of developmental biology, virology, biology of aging, and nutrition physiology. However, little is known about their physicochemical properties. Here, we report the phospholipid compositions and mechanical properties of cell membranes derived
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL
Bingpeng Yan et al.
International journal of molecular sciences, 20(23) (2019-11-30)
Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most common causes of hand, foot, and mouth disease. Severe EV-A71 and CV-A16 infections may be associated with life-threatening complications. However, the pathogenic mechanisms underlying these severe clinical and pathological features
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced

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