860074W

C18:0 GM3 (synthetic)

Avanti Research^™ - A Croda Brand 860074W, methanol solution

• Synonyme(s) : C18:0 GM3 Ganglioside (synthetic, ammonium salt)
• Formule empirique (notation de Hill): C₅₉H₁₁₁N₃O₂₁
• Numéro CAS: 1246353-19-4
• Poids moléculaire : 1198.52
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Essai: >99% (TLC)
• Forme: methanol solution
• Conditionnement: pkg of 1 × 1 mL (860074W-100ug)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 860074W
• Concentration: 0.1 mg/mL (860074W-100ug)
• Type de lipide: sphingolipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O)[C@@H](CO)O1.[NH4+]
• InChI: 1S/C59H108N2O21.H3N/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(69)61-40(41(66)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-77-56-51(73)50(72)53(45(37-64)79-56)80-57-52(74)55(49(71)44(36-63)78-57)82-59(58(75)76)34-42(67)47(60-39(3)65)54(81-59)48(70)
• Clé InChI: WFQOHDPRXSLGNK-BLVJLEROSA-N

Description

Description générale

Ganglioside monosialodihexosylganglioside (GM3) are membrane-bound glycosphingolipids (GSLs). It comprises a sialic acid residue and an oligosaccharide head structure. GM3 is present in milk and kidney cells. GM3 is the most widely present ganglioside in tissues.

Actions biochimiques/physiologiques

Ganglioside monosialodihexosylganglioside (GM3) modulates apoptosis, cell proliferation and differentiation. It is also essential for cellular signaling pathways, cell adhesion and mobility. GM3 prevents the action of fibroblast growth factor receptor. Low levels of ganglioside GM3 is associated with the pathogenesis of rheumatoid arthritis. GM3 maintains immunological functions by inhibiting cytokine production.

Conditionnement

2 mL Amber Glass Sealed Ampule (860074W-100ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup