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Key Documents

810227P

Avanti

C12-NBD Lactosyl Ceramide

Avanti Research™ - A Croda Brand 810227P, powder

Synonyme(s) :

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-lactosyl-β1-1′-sphingosine

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About This Item

Formule empirique (notation de Hill):
C48H81N5O16
Numéro CAS:
474943-06-1
Poids moléculaire :
984.18
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 50 μg (810227P-50ug)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 810227P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

C12-NBD Lactosyl ceramide is a fluorescent analog of biologically available compound lactosyl ceramide. Lactosyl ceramideis generally present on neutrophils and macrophages.

Actions biochimiques/physiologiques

Lactosyl ceramide is the major precursor for synthesis of various glycosphingolipids like oligoglycosylceramides and gangliosides. It is an important signaling molecule that is involved in adhesion, migration, cell proliferation and angiogenesis. Lactosyl ceramide is vital for osteoclastogenesis mediated by macrophage-colony stimulating factor.

Conditionnement

5 mL Amber Glass Screw Cap Vial (810227P-50ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Consulter la Bibliothèque de documents

T Iwamoto et al.
The Journal of biological chemistry, 276(49), 46031-46038 (2001-10-11)
Glycosphingolipids and their metabolites play important roles in a variety of biological processes. Several signal molecules are localized in a glycolipid-enriched microdomain on the cell surface, and their signals are regulated by the glycolipid composition. However, the function of glycolipids
W I Weis et al.
Annual review of biochemistry, 65, 441-473 (1996-01-01)
Lectins are responsible for cell surface sugar recognition in bacteria, animals, and plants. Examples include bacterial toxins; animal receptors that mediate cell-cell interactions, uptake of glycoconjugates, and pathogen neutralization; and plant toxins and mitogens. The structural basis for selective sugar
S Hakomori et al.
Journal of biochemistry, 118(6), 1091-1103 (1995-12-01)
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been implicated as playing major roles in cellular interactions and control of cell proliferation in multicellular organisms. These functional roles have been partially clarified through two types

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