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330678

Avanti

SM ELISA (Clear)

Avanti Research™ - A Croda Brand

Synonyme(s) :

SM ELISA, Brain Sphingomyelin ELISA Snoopers™, Clear, for use in absorbance applications

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.84

Forme

liquid

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Conditionnement

1 ea of 1 × (ELISA strip packaged in foil pouch)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

Avanti Lipid Snoopers™ are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods. Sphingomyelin (SM) is a sphingolipid present in central nervous system as a component of the myelin sheath and neuronal cells. It is synthesized from ceramide in Golgi. Acid sphingomyelinase (aSMase) degrades SM.
ELISA Snoopers™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
  • quantitative lipid-protein binding studies
  • assemble a 96-well plate using only the lipids of interest for binding studies
  • flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.


The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.

Actions biochimiques/physiologiques

Sphingomyelin (SM) participates in the inflammatory process and signalling pathways. It is a crucial regulator for myelin integrity, axon maturation, cognition and brain development. The SM to ceramide ratio is crucial, as high ceremide levels are implicated in depression. Altered levels of sphingomyelin due to sphingomyelinase deficiency results in Niemann–Pick disease.

Conditionnement

ELISA Strip Packaged in Foil Pouch (330678-1EA)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Sphingolipid metabolism in neural cells
van ED, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1758(12), 1978-1994 (2006)
Sphingolipids: membrane microdomains in brain development, function and neurological diseases
Olsen ASB and Faergeman NJ
Open Biology, 7(5), 170069-170069 (2017)
Sphingomyelin in brain and cognitive development: preliminary data
Schneider N, et al.
eNeuro (2019)
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)

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