QBD10631

Bis-MAL-Lysine-dPEG^®₄-TFP ester

• Synonyme(s) : Polyethylene glycol
• Formule empirique (notation de Hill): C₃₇H₄₅F₄N₅O₁₃
• Poids moléculaire : 843.77
• Numéro MDL: MFCD28385461
• Code UNSPSC : 12352108
• ID de substance PubChem : 329823944
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90%
• Forme: solid or viscous liquid
• Pertinence de la réaction: reagent type: cross-linking reagent; reactivity: thiol reactive
• Architecture des polymères: shape: linear; functionality: monofunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: O=C(C(NC(CCN1C(C=CC1=O)=O)=O)CCCCNC(CCN2C(C=CC2=O)=O)=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

Description

Caractéristiques et avantages

Bis-MAL-Lysine-dPEG^®₄-TFP ester is a unique crosslinker containing two maleimide groups, one on each amine of lysine, a 4-unit, single molecular weight dPEG^® spacer arm, and a 2,3,5,6-tetrafluorophenyl (TFP) ester. Each maleimide group reacts with a sulfhydryl group, and the TFP ester reacts with a free amine. The single molecular weight dPEG^® spacer is hydrophilic and non-immunogenic. This reagent can be used to modify or form conjugates with antibodies, antibody fragments, peptides, and small molecules.

Informations légales

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable