H1384

Hypotaurine

≥98% (TLC)

• Synonyme(s) : 2-Aminoethanesulfinic acid
• Formule empirique (notation de Hill): C₂H₇NO₂S
• Numéro CAS: 300-84-5
• Poids moléculaire : 109.15
• Numéro MDL: MFCD00038197
• Code UNSPSC : 12352100
• ID de substance PubChem : 57654233
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Pureté: ≥98% (TLC)
• Couleur: white to off-white
• Solubilité: H₂O: 100 mg/mL
• Chaîne SMILES: NCCS(O)=O
• InChI: 1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
• Clé InChI: VVIUBCNYACGLLV-UHFFFAOYSA-N

Description

Application

Hypotaurine has been used as a supplement in fertilization medium (Fert- tyrode albumin lactate pyruvate (TALP)), which used in in-vitro fertilization and evaluation of embryo development. It is also used as a H₂S scavenger.

Actions biochimiques/physiologiques

Hypotaurine, a cystamine analog, is the precursor for taurine synthesis. It can act as an antioxidant and singlet oxygen scavenger, thereby protecting cells from oxidative damage. Hypotaurine is reported to play an important role in the maintenance and stimulation of sperm motility and also in vitro fertilization and embryo development.

Antioxidant that binds hydroxyl radicals. Endogenous inhibitory neuromodulator that is blocked by strychnine and picrotoxin. Inhibits the Na²⁺-dependent transport of GABA and β-alanine. It is a degradation product of cysteine and a precursor of taurine.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves