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Principaux documents

923788

Sigma-Aldrich

HumaTein™ MSC bioink

derived from primary human mesenchymal stem cell culture, suitable for 3D bioprinting applications

Synonyme(s) :

3D bioprinting, 3DBP, ECM

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Composition

Bioink lyophilized powder

Impuretés

<0.12 EU/mg Endotoxin

Température de stockage

−20°C

Application

HumaTein™ MSC bioink is based on whole ECM derived from primary human BM-MSC culture, and it′s suitable for 3D bioprinting applications. Whole ECM consists of more than 300 components includes collagen family, laminin, fibronectin, glycosaminoglycans and reserves more than 500 cytokines in balanced composition that regulate cell phenotype and function for tissue homeostasis in development. HumaTein MSC provides a rich ECM environment to promote cellular proliferation. HumaTein MSC contains human extracellular matrix components including collagens, laminin, fibronectin, tenascin, elastin, and a number of proteoglycans and glycosaminoglycans.

The cell culture derived human whole ECM effectively recapitulates tissue micro-environment during development and in organotypic cell culture. It promotes cell growth and migration and has been shown to support the proliferation of many cell types, including human embryonic stem cells, neural stem cells, endothelial cells, MSC, pericytes, fibroblasts, hepatocytes, skeletal muscle cell, smooth muscle cell, and keratinocytes. This cell culture derived human whole ECM is not denatured nor chloroform sterilized. It provides for a more tissue-like environment, due to the 3D folding structure preserved ECM proteins, which provides scaffolding structure for cell attachment, growth and migration.

Informations légales

HumaTein is a trademark of Rokit Healthcare, Inc.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H317,H319

Classification des risques

Eye Irrit. 2 - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

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