900893

L-Homopropargylglycine hydrochloride

• Synonyme(s) : HPG
• Formule empirique (notation de Hill): C₆H₉NO₂ · HCl
• Numéro CAS: 98891-36-2
• Poids moléculaire : 163.60
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• Forme: powder or crystals
• Disponibilité: available only in USA
• Pf: 162 °C
• Température de stockage: −20°C
• Chaîne SMILES: O=C(O[H])[C@@](C([H])([H])C([H])([H])C#C[H])([H])N([H])[H].Cl[H]
• InChI: 1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)
• Clé InChI: SCGJGNWMYSYORS-UHFFFAOYSA-N

Description

Application

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Danger
• Mentions de danger: H242
• Conseils de prudence: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classification des risques: Self-react. C
• Code de la classe de stockage: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable