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764612

Sigma-Aldrich

Poly(D,L-lactide)

greener alternative

average Mn 5,000, PDI ≤1.1

Synonyme(s) :

PDLA, PLA, polyDL-lactide

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

solid

Poids mol.

average Mn 5,000

Caractéristiques du produit alternatif plus écologique

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Intervalle de dégradation

<6 months

Pf

264-270 °C

PDI

≤1.1

Autre catégorie plus écologique

Enabling

Température de stockage

2-8°C

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Catégories apparentées

Description générale

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

Application

Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
MKCL9077
MKCG2488
MKBX5311V
MKBS3411V
MKBL5073

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Poly(L-lactide) average Mn 40,000

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94829

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Poly(L-lactide) viscosity ~1.0&#160;dL/g, 0.1&#160;% (w/v) in chloroform(25&#160;°C)

Sigma-Aldrich

93578

Poly(L-lactide)

Poly(D-lactide) inherent viscosity ~1.2 dl/g

Sigma-Aldrich

67122

Poly(D-lactide)

Resomer&#174; R 203 H, Poly(D,L-lactide) acid terminated, Mw 18,000-24,000

Sigma-Aldrich

719943

Resomer® R 203 H, Poly(D,L-lactide)

Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Articles

Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

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