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746983

Sigma-Aldrich

Poly(styrene)-block-poly(acrylic acid)

average Mn 38,000, 20 wt. % PAA, PDI ≤1.3

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About This Item

Formule empirique (notation de Hill):
C4H6N(C8H8)m(C3H4O2)nH
Code UNSPSC :
12352100
Nomenclature NACRES :
NA.23

Forme

powder

Poids mol.

Mn 27,000-33,000 (polystyrene)
Mn 34,000-42,000 (total)
Mn 7,000-9,000 (poly(acrylic acid))
average Mn 38,000

PDI

≤1.3

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Application

Polystyrene-block-polyacrylic acid is a diblock copolymer used for making polymeric micelles/vesicles (polymersomes) and other encapsulation applications,. This PS-block-PAA copolymer is 20 wt. % AA; and should form micelles in water in the 30~50 nm range. The polystyrene degree of polymerization (DP) is 275 and the polyacrylic acid DP is 120.

Informations légales

Sold for research purposes only and subject to field restriction: see www.sigmaaldrich.com/raftlicense.  Patents: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111; W2010/8356.

Sold for research purposes only.  Not for use in humans.  Before opening or using this product, please read the following terms and conditions.  Use of this product shall constitute acknowledgement and acceptance of these terms and conditions.
Use of this product may be covered by one or more of the following US patents and corresponding claims outside the US: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111, and pending applications (W2010/8356).  For details contact Aldrich Chemical Company, Inc.

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Kaoutar Moumile et al.
Journal of clinical microbiology, 42(2), 923-924 (2004-02-10)
We describe a case of primary purulent culture-negative pericarditis caused by Neisseria meningitidis serogroup C occurring in an 8-month-old previously healthy boy, which was detected in pericardial fluid by broad-spectrum PCR amplification.
Dennis E Discher et al.
Science (New York, N.Y.), 297(5583), 967-973 (2002-08-10)
Vesicles are microscopic sacs that enclose a volume with a molecularly thin membrane. The membranes are generally self-directed assemblies of amphiphilic molecules with a dual hydrophilic-hydrophobic character. Biological amphiphiles form vesicles central to cell function and are principally lipids of

Articles

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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