512125

3-Pyridinylboronic acid

≥95.0%

• Synonyme(s) : 3-Pyridineboronic acid, 3-Pyridylboronic acid, Dihydroxy(3-pyridyl)borane, Pyridin-3-ylboronic acid
• Formule empirique (notation de Hill): C₅H₆BNO₂
• Numéro CAS: 1692-25-7
• Poids moléculaire : 122.92
• Numéro MDL: MFCD00674177
• Code UNSPSC : 12352103
• ID de substance PubChem : 24873612
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95.0%
• Forme: solid
• Pf: >300 °C (lit.)
• Chaîne SMILES: OB(O)c1cccnc1
• InChI: 1S/C5H6BNO2/c8-6(9)5-2-1-3-7-4-5/h1-4,8-9H
• Clé InChI: ABMYEXAYWZJVOV-UHFFFAOYSA-N

Description

Application

3-Pyridinylboronic acid can be used as a reagent for:

• Phosphine-free Suzuki-Miyaura cross-coupling reactions.
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation.
• N-arylation using copper acetylacetonate catalyst.
• Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes.

It can also be used to prepare:

• New linear poly(phenylpyridyl) chains by Suzuki coupling.
• Oligopyridyl foldamers as mimics of a-helix twist.
• Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists.
• Pyridine substituted pyridinium N-(2′-azinyl)aminides by reacting with dibromo pyridinium aminides via Suzuki coupling reaction.

Autres remarques

Contains varying amounts of anhydride

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)