422460
2-Thiazolecarboxaldehyde
97%
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About This Item
Formule empirique (notation de Hill):
C4H3NOS
Numéro CAS:
Poids moléculaire :
113.14
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
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Niveau de qualité
Pureté
97%
Forme
liquid
Indice de réfraction
n20/D 1.574 (lit.)
Point d'ébullition
61-63 °C/15 mmHg (lit.)
Densité
1.288 g/mL at 25 °C (lit.)
Température de stockage
2-8°C
Chaîne SMILES
O=Cc1nccs1
InChI
1S/C4H3NOS/c6-3-4-5-1-2-7-4/h1-3H
Clé InChI
ZGTFNNUASMWGTM-UHFFFAOYSA-N
Catégories apparentées
Description générale
2-Thiazolecarboxaldehyde is a thiazole aldehyde derivative. It undergoes Baylis–Hillman reaction with methyl acrylate catalyzed by DABCO (1,4-diazabicyclo[2.2.2]octane). The reaction mechanism has been studied by electrospray ionization mass spectrometry (ESI-MS).
Application
2-Thiazolecarboxaldehyde may be used as a reactant in the following syntheses:
- Benzothiazine N-acylhydrazones, having potential antinociceptive and anti-inflammatory activity.
- Thiazole-2-yl-(amino)methylphosphonate diethyl esters.
- Imino ester by reacting with L-leucine t-butyl ester hydrochloride.
Useful building block for taxane analogs.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
154.4 °F - closed cup
Point d'éclair (°C)
68 °C - closed cup
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