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2-Amino-5-methylthiazole

Name: 2-Amino-5-methylthiazole
Brand: ALDRICH

98%

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About This Item

Formule empirique (notation de Hill):

C₄H₆N₂S

Numéro CAS:

7305-71-7

Poids moléculaire :

114.17

Numéro Beilstein :

109603

Numéro MDL:

MFCD00078317

Code UNSPSC :

12352100

ID de substance PubChem :

24863751

Nomenclature NACRES :

NA.22

Pureté

98%

Forme

powder

Pf

93-98 °C (lit.)

Chaîne SMILES

Cc1cnc(N)s1

InChI

1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)

Clé InChI

GUABFMPMKJGSBQ-UHFFFAOYSA-N

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Description générale

2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).

Application

2-Amino-5-methylthiazole may be used in the preparation of acrylamide monomer, 5-methyl-2-thiozyl methacrylamide (MTMAAm).

2-Amino-5-methylthiazole may be used in the preparation of mixed-ligand dien-Cu(II) complexes (dien=diethylenetriamine). It may be used in the preparation of a new series of Schiff mono/dibase coordination compounds, having potential anticancer and antibacterial activities.

Pictogrammes

GHS08,GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H302,H373,H410

Conseils de prudence

P260 - P264 - P270 - P273 - P301 + P312 - P314

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Synthesis and characterization of new chelating resin: adsorption study of copper (II) and chromium (III) ions.

Sacmaci S, et al.

Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 47(6), 552-557 (2010)

Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.

C A Bolos et al.

Journal of inorganic biochemistry, 88(1), 25-36 (2001-12-26)

The reaction of [Cu(dien)NO(3)]NO(3) with 2-amino-5-methylthiazole (2A5MT), 2-amino-2-thiazoline (2A-2Tzn), imidazole (im), N,N'-thiocarbonyldiimidazole (Tcdim), 2-aminothiazole (2AT) and 2-ethylimidazole (2Etim), gave a new series of mixed-ligand compounds of the general formula [Cu(dien)(B)NO(3))]NO(3); (dien, diethylenetriamine; B, 2A5MT, 2A-2Tzn, im, Tcdim, 2AT and 2Etim).

Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: synthesis, characterization, antiproliferative and antibacterial studies. Crystal structure of CudienOOCl2.

A Th Chaviara et al.

Journal of inorganic biochemistry, 98(8), 1271-1283 (2004-07-24)

A new series of coordination compounds of the starting materials [Cu(dienX(2)Y(2))] and their adducts [Cu(dienXXY(2))(2a-5mt)] (where dien=diethylenetriamine, dienXX=Schiff bases of diethylenetriamine with 2-furaldehyde or 2-thiophene-carboxaldehyde, X=O, S, Y=Cl, Br, NO(3) and 2a-5mt=2-amino-5-methylthiazole) were synthesized by stepwise reactions and their structures

Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole.

E Pontiki et al.

Journal of enzyme inhibition and medicinal chemistry, 23(6), 1011-1017 (2008-11-14)

Highly reactive radicals are implicated in many pathological conditions. The quest for radical scavengers or antioxidants, spans the previous decades. A new series of complexes of the type [Cu (dien) (2a-2tzn) Y(2)] and [Cu (dienXXY(2)) (2a-5mt)] and of the type

Ratio derivative spectrophotometric method for the determination of some oxicams in presence of their alkaline degradation products.

Taha EA, et al.

Scientia Pharmaceutica, 71(4), 303-320 (2003)

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