STAT5A
signal transducer and activator of transcription 5A
Synonymes:
MGF, STAT5
Espèce(s):
Human STAT5A (6776), Mouse Stat5a (20850), Rat Stat5a (24918), dog STAT5A (490968), Horse STAT5A (100052904), domestic cat STAT5A (101090913), cow STAT5A (282375), sheep STAT5A (443419), naked mole-rat Stat5a (101723770), domestic guinea pig Stat5a (100716811)
ID UniProtKB:
ID du gène:
- Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- Mouse(20850) signal transducer and activator of transcription 5A
- Rat(24918) signal transducer and activator of transcription 5A
- dog(490968) signal transducer and activator of transcription 5A
- Horse(100052904) signal transducer and activator of transcription 5A
- domestic cat(101090913) signal transducer and activator of transcription 5A
- cow(282375) signal transducer and activator of transcription 5A
- sheep(443419) signal transducer and activator of transcription 5A
- naked mole-rat(101723770) signal transducer and activator of transcription 5A
- domestic guinea pig(100716811) signal transducer and activator of transcription 5A
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ELISA
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
Espèces réactives
bovine, human, mouse, rat, sheep
Application
western blot
Anti-Phospho-STAT5A-Y694 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 94-10C-9-10C-2, rabbit monoclonal, clone 94-10C-9-10C-2, from rabbit,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody, serum, Upstate®,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal, culture supernatant, clone A11W, from rabbit,
Espèces réactives
bovine, chimpanzee, human, mouse, rat
Application
western blot
Proteins
Référence du produit
Description
Espèce(s)
STAT5, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human