NR3C2
nuclear receptor subfamily 3, group C, member 2
Synonymes:
MCR, MLR, MR, NR3C2VIT
Espèce(s):
Human NR3C2 (4306), Mouse Nr3c2 (110784), Rat Nr3c2 (25672), Zebrafish nr3c2 (562171), dog NR3C2 (475461), cow NR3C2 (280861), cow NR3C2 (537614), Horse NR3C2 (100062570), domestic cat NR3C2 (101081977), chicken NR3C2 (374131) ...Plus
ID UniProtKB:
ID du gène:
- Human(4306) Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(110784) nuclear receptor subfamily 3, group C, member 2
- Rat(25672) nuclear receptor subfamily 3, group C, member 2
- Zebrafish(562171) nuclear receptor subfamily 3, group C, member 2
- dog(475461) nuclear receptor subfamily 3, group C, member 2
- cow(280861) nuclear receptor subfamily 3, group C, member 2
- cow(537614) nuclear receptor subfamily 3, group C, member 2
- Horse(100062570) nuclear receptor subfamily 3, group C, member 2
- domestic cat(101081977) nuclear receptor subfamily 3, group C, member 2
- chicken(374131) nuclear receptor subfamily 3, group C, member 2
- sheep(101107046) nuclear receptor subfamily 3, group C, member 2
- domestic guinea pig(100735309) nuclear receptor subfamily 3, group C, member 2
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Deoxycorticosterone acetate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Spironolactone Related Compound A, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Mineralocorticoid Receptor Antibody, clone 6G1, clone 6G1, from mouse,
Espèces réactives
mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NR3C2 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human, rabbit
Application
immunohistochemistry
western blot
western blot
Anti-Mineralocorticoid Receptor Antibody, clone 2D6, clone 2D6, from mouse,
Espèces réactives
rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NR3C2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-NR3C2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
horse, human
Application
western blot