MTOR
mechanistic target of rapamycin (serine/threonine kinase)
Synonymes:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Espèce(s):
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...Plus
ID UniProtKB:
ID du gène:
- Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
- Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
- Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
- Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
- cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
- Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
- domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
- dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
- fruit fly(36264) Megator
- chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
- Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
- naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
- domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
- Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
- sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-mTOR (Ser2448) Antibody, Upstate®, from rabbit,
Espèces réactives
human
Application
western blot
Anti-mTOR Antibody, clone 21D8.2, clone 2ID8.2, from mouse,
Espèces réactives
human, mouse
Application
immunocytochemistry
western blot
western blot
Anti-phospho-mTOR (pSer2481) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Monoclonal Anti-mTOR antibody produced in mouse, clone GT6611, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Espèce(s)
human
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)