MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
Synonymes:
MARCH-I, RNF171
Espèce(s):
Human MARCH1 (55016), Mouse March1 (72925), Rat March1 (361135), chicken MARCH1 (422420), cow MARCH1 (617247), dog MARCH1 (612618), domestic cat MARCH1 (101098865), sheep MARCH1 (101106078), naked mole-rat March1 (101724772), domestic guinea pig March1 (100722498)
ID UniProtKB:
ID du gène:
- Human(55016) Summary: MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]
- Mouse(72925) membrane-associated ring finger (C3HC4) 1
- Rat(361135) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- chicken(422420) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- cow(617247) membrane-associated ring finger (C3HC4) 1
- dog(612618) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic cat(101098865) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- sheep(101106078) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- naked mole-rat(101724772) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic guinea pig(100722498) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MARCH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-MARCH1 antibody produced in mouse, clone 3D2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-MARCH1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot